Nanoscale architecture of a VAP A OSBP tethering complex at membrane contact sites Nature Communications HDL and LDL particles differ in several ways, including their: Role in heart health Role in treatment Healthy levels Key differences: HDL: Removes excess cholesterol from your arteries, limiting plaque buildup Not Cholesterol transport in the late endocytic pathway: Roles of ORP family proteins ScienceDirect Lipids Whole Health Library