Best Practices in the Diagnosis and Treatment of Ventilator Associated Pneumonia REGARD VAP ICU REACH VAP Bundle Ventilator Associated Pneumonia Ventilator Associated Pneumonia ( VAP) is a lung infection that occurs in patients who are on mechanical ventilation for more than 48 hours. A VAP bundle is a set of VAP Ventilator Associated Pneumonia Preventions Ventilator Acquired Pneumonia VAP Preventions